Crystallophore, a unique nucleating and phasing agent for biocrystallography

Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence.

Macromolecular crystallography suffers from two major issues: getting well-diffracting crystals and solving the phase problem inherent to large macromolecules. Here, we describe the first example of a lanthanide complex family named "crystallophore" (Xo4), which contributes to tackling both bottlenecks. This terbium complex, Tb-Xo4, is an appealing agent for biocrystallography, combining the ex...

passivity in waiting for godot and endgame: a psychoanalytic reading

this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...

Crystallophore: a versatile lanthanide complex for protein crystallography combining nucleating effects, phasing properties, and luminescence† †Electronic supplementary information (ESI) available: General procedures, Tb–Xo4 synthesis, Fig. S1–S11 and Tables S1–S4. See DOI: 10.1039/c7sc00758b

Unique Hypocalcemic Agent

Hypocalcemia has been observed in patients receiving WR-2721 IS-,2-(3-aminopropylamino)-, ethylphosphorothioic acid]. WR2721 is a compound that, after being dephosphorylated, provides protection of normal tissues against radioand chemotherapy. The hypocalcemic response was accompanied by a decrease in the plasma level of parathyroid hormone (PTH) and by hypomagnesemia. Our present studies in ra...

A unique continuous solution for the Bagley-Torvik equation

In this paper the Bagley-Torvik equation as a prototype fractional differential equation with two derivatives is investigated by means of homotopy perturbation method. The results reveal that the present method is very effective and accurate.